The catalytic performance of self- developed non-hydrogen-dewaxing catalyst (FC-DB) was evaluated, and the hydrocracking tail oil was used as feed stock. The influence of reaction temperature and space velocity on the yield and pouring point of base oil was investigated. The relationships between yield, pouring point and operation conditions were determined by polynary quadratic regression, and the optimum operation conditions were determined by non-linear programming. The reaction temperature is 400 ℃ and space velocity is 1.2 h-1. At this time, the yield and pouring point of base oil respectively are 92.53% and -20 ℃, approximately dropping 53 ℃. The qualify of base oil obtained under above optimum operation conditions was analyzed, and the base oil can be used as premium lubricant base oil because of its high viscosity index, low pouring point, acidity and residue carbon.